VIII FVIII MULTISPECIFIC ANTIGEN-BINDING MOLECULES HAVING BLOOD COAGULATION FACTOR VIII FVIII COFACTOR FUNCTION-SUBSTITUTING ACTIVITY AND PHARMACEUTICAL FORMULATIONS CONTAINING SUCH A MOLECULE AS AN ACTIVE INGREDIENT
It has been successful to find bispecific antibodies that do not increase FIX activation inhibitory activity and also increase FVIII carrier function replacement activity.FIX 활성화 저해 활성은 상승시키지 않고, 또한 FVIII 보인자 기능 대체 활성을 상승시키는 이중특이성 항체를 발견하는 것에 성공했다.