Inc.;President and Fellows of Harvard College;Dana-Farber Cancer Institute;Dana-Farber Cancer Institute, Inc.
发明人:
Walesnky, Loren D.,Korsmeyer, Stanley J.,Verdine, Gregory
申请号：
AU2015201062
公开号：
AU2015201062B2
申请日:
2015.03.02
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
#$%^&*AU2015201062B220170309.pdf#####ABSTRACT Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking ("hydrocarbon stapling") moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
