您的位置: 首页 > 农业专利 > 详情页

PHARMACEUTICAL AEROSOL DRUGS OF FORMOTEROL AND BECLOMETASONE DIPROPIONATE
专利权人:
КЬЕЗИ ФАРМАЧЕУТИЧИ С.П.А. (IT)
发明人:
БРАМБИЛЛА Гаэтано (IT)
申请号:
RU2012112454/15
公开号:
RU2012112454A
申请日:
2010.09.27
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A pharmaceutical aerosol preparation intended for use in metered-dose inhalers (BITs), comprising (a) from 0.001 to 0.05% w / w. a pharmaceutically acceptable salt or solvate of formoterol; (b) from 0.05 to 0.16% w / w. beclomethasone dipropionate (BDP); (c) from 2.0 to 4.8% w / w. ethanol; (d) HFA 134a characterized in that HFA 134a is the only propellant and the formoterol salt is suspended in micronized form, while the corticosteroid is completely dissolved. The preparation according to claim 1, comprising, as active ingredients, only a combination of formoterol salt and beclomethasone dipropionate. The drug according to claim 1 or 2, in which the salt of formoterol is selected from the group of fumarate, maleate, xinafoate and pamoate. The drug according to claim 3, in which the salt of formoterol is a fumarate dihydrate. The drug according to claim 1, in which the amount of ethanol is from 2.5 to 4.5% wt./wt. 6. The drug according to claim 5, in which the specified amount is from 2.5 to 4.0% wt./wt. 7. A metered-dose inhaler comprising a container filled with a pharmaceutical preparation according to any one of claims 1 to 6, and a metering valve for delivering therapeutically effective doses of the active ingredients. The metered-dose metered-dose inhaler according to claim 7, wherein the dose of formoterol salt is 6 or 12 mcg. A metered-dose inhaler according to claim 7 or 8, wherein the dose of beclomethasone dipropionate is 50 or 100 μg. Use of a corticosteroid in an aerosol inhalation preparation comprising a pharmaceutically acceptable salt or solvate of formoterol as an active ingredient and a mixture of HFA 134 and ethanol as a carrier to reduce solubility1. Фармацевтический аэрозольный препарат, предназначенный для применения в дозирующих ингаляторах под давлением (ДИД), включающий(a) от 0,001 до 0,05% мас./мас. фармацевтически приемлемой соли или сольвата формотерола;(b) от 0,05 до 0,16% мас./мас. беклометазона дипропионата (БДП);(c) от 2,0 до 4,8%
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充