PROBLEM TO BE SOLVED: To provide a substance useful for GLP-1 secretion promotion, glucagon secretion depression, appetite depression, or prophylaxis and/or improvement or the like of a disease or a state such as postprandial hyperglycemia, diabetes and the like.SOLUTION: The GLP-1 secretion promoter contains Quillai or an extract thereof as an effective constituent. An glucagon secretion depressant contains the Quillai or the extract thereof as an effective constituent. An appetite depressant contains the Quillai or the extract thereof as an effective constituent. A medicine for the prophylaxis and/or improvement of the postprandial hyperglycemia contains the Quillai or the extract thereof as an effective constituent. A medicine for the prophylaxis and/or improvement of the diabetes contains the Quillai or the extract thereof as an effective constituent.COPYRIGHT: (C)2012,JPO&INPIT【課題】GLP-1分泌促進、グルカゴン分泌抑制、食欲抑制、又は食後高血糖、糖尿病等の疾患若しくは状態の予防及び/又は改善等に有用な物質の提供。【解決手段】キラヤ又はその抽出物を有効成分とするGLP-1分泌促進剤。キラヤ又はその抽出物を有効成分とするグルカゴン分泌抑制剤。キラヤ又はその抽出物を有効成分とする食欲抑制剤。キラヤ又はその抽出物を有効成分とする食後高血糖予防及び/又は改善剤。キラヤ又はその抽出物を有効成分とする糖尿病予防及び/又は改善剤。【選択図】なし