INHIBITEUR DE MICRO-ARN S-TUD STRUCTURELLEMENT AMÉLIORÉ

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专利权人:

Genedesign, Inc.;The University Of Tokyo

发明人:

申请号：

EP16845971.7

公开号：

EP3351632A4

申请日:

2016.09.16

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

The present invention pertains to the improvement of a miRNA inhibitor (a synthesized Tough Decoy (S-TuD)). The present invention provides a miRNA inhibitory complex including RNA or an analog thereof, wherein the RNA inhibitory complex includes at least one double-stranded structure and a miRNA binding sequence, each of two strands of the miRNA binding sequence being bound to two strands of at least one end of the double-stranded structure, and the miRNA inhibitory complex further includes at least one crosslinked nucleic acid.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/