1. This specification refers to the compound, its use and preparation method, and the compound forming the compound. 1. Claim 1: a formula compound (1),where R¹ is H； R² is selected from the group consisting of: CH₂-cyclohexyl, wherein the cyclohexyl is optionally substituted with OH； 3-hydroxyamantan-1-yl； and C₃₋₆ cycloalkyl optionally substituted with 1, 2 or 3 substituents, each independently selected from the group consisting of: OH, halogen, C₁₋₆-alkyl,haloalkyl C₁₋₆,O-asphalt c83218c31832626；Cn, No. 8310； r8311；NR -C (O) H NR -C (O) -alquilo CNr.831222-c (o) - halide c83221；831222-c (o) - o-asphalt c832138；NR⁸-C (O) -alq C₁₋₆-OH, NR⁸-C (O) -alq C₁₋₆-NR⁶R⁷ and NR⁸-C (O) -C (R³) = CR⁴ (R⁵)；where R³ is selected from the group consisting of: H, CN, halogen, C₁₋₆ haloalkyl and C₁₋₆ alkyl；R⁴ and R⁵ are each independently selected from the group consisting of: H； alq C₀₋₆-NR⁶R⁷；Cq-al-C--alkyl；C₃₋₆ cycloalkyl；heterocycloalkyl optionally substituted with C₁₋₆-alkyl；and linker-PEG-biotin； R⁶ and R⁷ are each independently selected from the group consisting of: H, C₁₋₆ alkyl,C / 8333o 8334h 696 CN； 6966 r831222 es h； or R 1 and R 2,They combine with nitrogen atoms to form a pyrethroid ring, which is replaced by NR8310R8311；wherein R⁶ and R⁷ are each independently selected from the group consisting of H； C₁₋₆-alkyl；NR⁸-C (O) -C₁₋₆ alkyl；y NR -C (O) -C (R) 3DCR (R)where R³ is H or CN； R⁴ is H； and R⁵ is H or cyclopropyl； A is selected from the group consisting of: pyridyl； phenyl； pyrimidinyl； pyrazinyl； pyridin-2 (1H) -one； and pyridazinyl； wherein A is optionally substituted with 1, 2 or 3 substituents, each independently selected from the group consisting of halogen, C₁₋₆-alkyl,C₁₋₆ haloalkyl and C₁₋₆ O-alkyl；E selected from the group consisting of O, link and ch832222；G selected from: H； halogen； c832131； anda. Halogenated tar c83218d31832626；NH (C₁₋₆-alkyl)；C₃₋₆ cycloalkyl；phenyl； pyrimidinyl； pyridyl； pyridazinyl； pyridin-2 (1H) -one； heterocycloalkyl containing an
