N-(3-heteroarylaryl)-4-arylarylcarboxamides and Analogs as Hedgehog Pathway Inhibitors and Use Thereof

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专利权人:

IMPACT Therapeutics; Inc.

发明人:

Suixiong Cai,Ye Tian,Sishun Kang,Zheng Meng,Chengyun Gu,Feng Yin,Shengzhi Chen,Yang Zhang,Xiuyan Zhang,Hongqiang Fei,Dongmei Wang

申请号：

US14415293

公开号：

US20150191460A1

申请日:

2013.07.19

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Disclosed are novel N-(3-heteroarylaryl)-4-arylarylcarboxamides and analogs thereof, represented by the Formula I: wherein C cyclic group, D1-D4, Q1, Q2, R5 are defined herein. Compounds having Formula (I) are hedgehog pathway inhibitors. Therefore, compounds of the invention may be used to treat clinical conditions that are responsive to the inhibition of hedgehog activity, such as cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/