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SMALL MOLECULE CANCER TREATMENTS THAT CAUSE NECROSIS IN CANCER CELLS BUT DO NOT AFFECT NORMAL CELLS
专利权人:
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
发明人:
Matthew R. Pincus,Josef Michl,Ehsan Sarafraz-Yazdi
申请号:
US16661036
公开号:
US20200038471A1
申请日:
2019.10.23
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A method of treating cancer in a subject, including: providing a subject having a plurality of cancer cells; and administering to the subject, a therapeutically effective amount of a composition including: an HDM-2 binding component; and a membrane resident component, the membrane resident component bound to the HDM-2 binding component. Also provided are a method of selectively necrosing cancer cells, a method of causing membranolysis in cancer cells, and a cancer treatment composition.
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