Pyrazole (4.3-d) pyridine compounds, quinase inhibitors； pharmacological synthesis； compounds used in the treatment of respiratory diseases and disorders
ALMSTETTER MICHAEL,TREML ANDREAS,TRAUBE NADINE,THORMANN MICHAEL
申请号：
CL2013003051
公开号：
CL2013003051A1
申请日:
2013.10.21
申请国别(地区):
CL
年份:
2014
代理人:
摘要：
The present invention relates to novel compounds of formula (I) that are capable of inhibiting one or more kinases, especially SYK (Spleen Tyrosine Kinase), LRRK2 (Leucine-rich repeat kinase 2) and/or MYLK (Myosin light chain kinase) or mutants thereof. The compounds find applications in the treatment of a variety of diseases. These diseases include autoimmune diseases, inflammatory diseases, bone diseases, metabolic diseases, neurological and neurodegenerative diseases, cancer, cardiovascular diseases, allergies, asthma, alzheimer's disease, parkinson's disease, skin disorders, eye diseases, infectious diseases and hormone-related diseases.COMPUESTOS DERIVADOS DE PIRAZOLO (4.3-D) PIRIMIDINAS, INHIBIDORES DE QUINASA； COMPOSICION FARMACEUTICA； Y USO PARA EL TRATAMIENTO DE ENFERMEDADES Y TRASTORNOS DEL APARATO RESPIRATORIO
