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תרכובות אורגניות הפעילות כאנטגוניסטים לקולטנים ניקוטיניים ותכשירי רוקחות המכילים אותן
专利权人:
INTRA-CELLULAR THERAPIES INC.
发明人:
申请号:
IL23003613
公开号:
IL230036A
申请日:
2013.12.19
申请国别(地区):
IL
年份:
2016
代理人:
摘要:
It is an object of the present invention that the novel nicotinic receptor antagonists disclosed herein may be used in a broad array of clinical or medicinal facets. For example, it is a contemplated use of the present invention that the novel nicotinic receptor antagonists be used to inhibit the growth cycle of non-small cell lung cancer cells. Without being bound by theory, it is an object of the present invention that the nicotinic receptor antagonists disclosed herein are believed to possess reversible binding properties. Moreover, the compounds of the present invention are selective for 0.7 nAChR. For example, the compounds of the present invention are not believed to bind to 0.4 (32 nAChR neuromuscular receptors. It is also contemplated that the nicotinic receptor antagonists of the present invention will be used as a counter measure to treat exposure, or potential exposure, to a wide array of potential neurotoxins.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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