Jean-Marie Lehn,Yves Claude Nicolau,Srinivasu Pothukanuri,Adam Brockman,John Hey,Jeremy Yu
申请号：
US13897113
公开号：
US20140142052A1
申请日:
2013.05.17
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides phosphorylated and pyrophosphate derivatives of polyols, and structural derivatives of these compounds, and provides pharmaceutical compositions comprising the same. The compounds and compositions disclosed herein have various biological activities, including for example, as allosteric effectors of hemoglobin and/or as kinase inhibitors. The present invention further provides methods for therapy in human or mammalian patients, and methods for synthesis of biologically active compounds and their intermediates.
