Pre-filled small volume syringe for intravitreal injection to treat e.g. ocular disease, has plunger including contact surface to contact stopper, and backstop with projections, where syringe is filled with growth factor antagonist fluid
SIGG JUERGEN,JUERGEN SIGG,ROYER CHRISTOPHE,CHRISTOPHE ROYER,BRYANT ANDREW MARK,ANDREW MARK BRYANT,BUETTGEN HEINRICH MARTIN,HEINRICH MARTIN BUETTGEN,PICCI MARIE,MARIE PICCI
申请号：
FR1350671
公开号：
FR2983077A1
申请日:
2013.01.25
申请国别(地区):
FR
年份:
2013
代理人:
摘要：
The syringe (1) has a stopper arranged within a body (2) such that a front surface of the stopper and the body define a variable volume chamber from which a fluid is expelled though an outlet of the body, and a backstop (6) including two finger projections. A plunger (4) comprises a plunger contact surface to contact the stopper such that the plunger forces the stopper towards an outlet end. The syringe is filled with a vascular endothelial growth factor (VEGF) antagonist fluid of about 0.15-0.175 ml containing a non-antibody VEGF antagonist aflibercept at a concentration of 40 mg/ml. The syringe comprises a syringe barrel filled with silicone oil of 100 microgram.La présente invention concerne une seringue, en particulier une seringue de petit volume telle qu'une seringue appropriée pour les injections ophtalmiques.
