PHENYL [A]INDOLE[2,3-G]QUINOLIZINE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS THEREOF

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专利权人:

CHINESE ACADEMY OF SCIENCES;SHANGHAI INSTITUTE OF MATERIA MEDICA

发明人:

LIU, Hong,WANG, Yiping,ZHAO, Fei,ZHAO, Jing,WANG, Jiang,XI, Cong,WU, Chenglin,SHEN, Hao,HAN, Xu,JIANG, Hualiang,CHEN, Kaixian

申请号：

SG11201808207R

公开号：

SG11201808207RA

申请日:

2017.03.29

申请国别(地区):

SG

年份:

2018

代理人:

摘要：

The present invention relates to phenyl [a]indole[2,3-g]quinolizine compounds represented by formula (I), a preparation method therefor, a pharmaceutical composition, and applications thereof. Specific applications are applications in the preparation of drugs for treating diseases related to a proprotein convertase subtilisin Kexin-9 (PCSK9), comprising the applications in the preparation of drugs for treating hyperlipemia, hypercholesterolemia, hypertriglyceridemia, fatty liver deformation, atherosclerosis, obesity and other metabolic diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/