Maria Trulsson;Ann-Kristin Mossberg;Catharina Svanborg;Petter Storm;Kenneth Hun Mok;Chin Shing Ho
发明人:
Catharina Svanborg,Kenneth Hun Mok,Maria Trulsson,Ann-Kristin Mossberg,Petter Storm,Chin Shing Ho
申请号:
US13988878
公开号:
US09085643B2
申请日:
2011.11.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A biologically active complex comprising either a polypeptide having the sequence of a variant of a naturally occurring protein, wherein said polypeptide is at least partially unfolded as compared to the said naturally occurring protein; or a peptide of up to 50 amino acids, for instance a fragment of the naturally occurring protein or a variant thereof; and a pharmaceutically acceptable salt of a fatty acid or lipid. The complexes of the invention demonstrate a novel mode of action, that gives rise to opportunities for the development of further active agents and screening methods.