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Reducing the risk of human and anti-human antibodies through V gene manipulation
专利权人:
发明人:
申请号:
EP11186502.8
公开号:
EP2418224A3
申请日:
2005.03.17
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present embodiments relate to methods of identifying and creating human, or humanized antibodies that possess a reduced risk of inducing a Human Anti-Human Antibody (HAHA) response when they are applied to a human host. Other methods are directed to predicting the likelihood of a HAHA response occurring. Methods for screening for anti-HAHA compounds are also included.
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