UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION; INC.
发明人:
COPIK, ALICJA,REDDY, VIJAY,OYER, JEREMIAH
申请号:
CA2877968
公开号:
CA2877968A1
申请日:
2013.06.28
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The application provides new compositions and methods for stimulating the production of natural killer (NK) cells in a subject. NK cells can be selectively expanded with a combination of stimulating ligands. Methods and compositions for the administration of stimulatory ligands modified to self-insert into tumor cells, thereby stimulating an increase in the number of NK cells in proximity to a tumor, are also described.