This invention describes a method for processing pressure signals derivable from locations inside or outside a human or animal body or body cavity. Different aspects of the invention relate to a method for optimal differentiating between cardiac beat- and artifact-induced pressure waves, a method for obtaining new and improved information from said pressure signals, a method for obtaining signals predicting pressures inside a body or body cavity from pressure signals outside said body or body cavity. In particular, this invention describes a method for modifying individual continuous non-invasive pressure-related signals into signals highly predictable of the corresponding invasive pressure-related signals based on already established relationships that can be used for formula-based adjustments of individual signals solely obtained by a non-invasive approach.