Enhanced affinity T cell receptors and methods for making the same

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专利权人:

Fred Hutchinson Cancer Research Center

发明人:

Schmitt, Thomas M.,Greenberg, Philip D.

申请号：

AU2018260963

公开号：

AU2018260963A1

申请日:

2018.11.09

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

#$%^&*AU2018260963A120181129.pdf#####1002361284 ABSTRACT The present disclosure provides methods for generating enhanced affinity T cell receptors by agonist selection of hematopoietic progenitor cells expressing an antigen specific TCRa cultured with stromal cells expressing Delta-like-I or Delta-like-4, compositions prepared from such methods, and uses of thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/