INHIBITEURS DE MTOR KINASE ET LEUR EMPLOI DANS LES CAS D'INDICATIONS ONCOLOGIQUES ET POUR DES MALADIES EN RAPPORT AVEC LA VOIE MTOR/P13K/AKT

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专利权人:

SIGNAL PHARMACEUTICALS; LLC

发明人:

ELSNER, JAN,HARRIS, ROY L.,LEE, BRANDEN,MORTENSEN, DEBORAH,PACKARD, GARRICK,PAPA, PATRICK,PERRIN-NINKOVIC, SOPHIE,RIGGS, JENNIFER,SANKAR, SABITA,SAPIENZA, JOHN,SHEVLIN, GRAZIELLA,TEHRANI, LIDA,XU, WEI

申请号：

CA2740975

公开号：

CA2740975C

申请日:

2009.10.27

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Provided herein are Heteroaryl Compounds having the following structure: R2N(I) or (II) wherein R1 -R4 are asdefined herein, compositions comprising an effective amount of a HeteroarylCompound and methods for treating or preventingcancer, inflammatory conditions, immunological conditions, neurodegenerativediseases, diabetes, obesity, neurological disorders,age-related diseases, or cardiovascular conditions, comprising administeringan effective amount of a Heteroaryl Compound to apatient in need thereof.

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