James F Smothers;Michael R Comeau;Bo-Rin P Yoon;Christopher Mehlin
发明人:
Michael R Comeau,James F Smothers,Bo-Rin P Yoon,Christopher Mehlin
申请号:
US13438739
公开号:
US09284372B2
申请日:
2012.04.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present disclosure provides compositions and methods relating to antigen binding proteins which bind to human thymic stromal lymphopoietin (TSLP), including antibodies. In particular embodiments, the disclosure provides fully human, humanized and chimeric anti-TSLP antibodies and derivatives of such antibodies. The disclosure further provides nucleic acids encoding such antibodies and antibody fragments and derivatives, and methods of making and using such antibodies including methods of treating and preventing TSLP-related inflammatory and fibrotic disorders.