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THE USE OF ANTIOXIDANTS TO PREVENT OXIDATION AND REDUCE DRUG DEGRADATION IN DRUG ELUTING MEDICAL DEVICES
专利权人:
CORDIS CORPORATION
发明人:
FENNIMORE, ROY R., JR.
申请号:
CA2504258
公开号:
CA2504258C
申请日:
2005.04.14
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
There is described herein a drug eluting medical device. In an aspect, thedevicecomprises an implantable intraluminal structure a first polymeric solution adrug intherapeutic dosages, incorporated into the first polymeric solution creating aresultingmixture a separate and distinct antioxidant incorporated into the resultingmixture tosubstantially hinder degradation of the drug through oxidation, therebycreating a basecoat with the antioxidant mixed or comingled with the drug in the base coat,the basecoat being affixed to at least a portion of the implantable intraluminalstructure and asecond polymeric solution forming a top coat affixed to the base coat.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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