Susan M. Freier,Frank Rigo,Mark Dockrell,Felicia Heidibrecht
申请号：
US14403953
公开号：
US20150291955A1
申请日:
2013.06.03
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Provided are compounds comprising oligonucleotides complementary to a fibronectin transcript. Certain such compounds are useful for hybridizing to a fibronectin transcript, including but not limited to a fibronectin transcript in a cell. Such hybridization results in modulation of splicing of the fibronectin transcript. Such compounds are used to treat one or more symptoms associated with fibrosis. Such compounds are used to treat one or more symptoms associated with renal fibrosis.
