GRUBER, HARRY E,JOLLY, DOUGLAS,PEREZ, OMAR,LOGG, CHRISTOPHER R
申请号:
NZ59207009
公开号:
NZ592070A
申请日:
2009.09.26
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is an isolated polynucleotide comprising a human codon optimized polynucleotide comprising a first coding sequence encoding a polypeptide of SEQ ID NO: 4 (a yeast cytosine deaminase triple mutant), wherein the polypeptide comprises cytosine deaminase (CD) activity.