Gursharan S. Chhatwal,Patric D. Nitsche-Schmitz,Katrin Dinkla,Vanessa Barroso
申请号：
US12302969
公开号：
US08956612B2
申请日:
2007.06.01
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to a streptococcal octapeptide AXYLXXLN, and preferably to the octapeptide AXYLZZLN, designated as peptide associated with rheumatic fever (PARF) that, through its interaction with human collagen, plays a crucial role in the pathogenesis of rheumatic fever. PARF therefore represents a marker for rheumatic fever associated strains and provides a target for therapies, and in particular preventive therapies.
