University of Yamanashi;School Juridical Person The Kitasato Institute;Nipro Corporation
发明人:
申请号：
EP14897191.4
公开号：
EP3167919A1
申请日:
2014.07.08
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
A blood purifier comprises hollow fiber membranes allowing blood to flow inside and allowing a dialysing fluid or a filtrated fluid to flow outside. The hollow fiber membrane has an effective length of 10 mm or more and 150 mm or less. A maximum value of a permeation flux Jv obtained by dividing a volume of a permeate fluid permeating through the hollow fiber membranes by a membrane area of the hollow fiber membranes and time, is represented as Jvmax. A linear velocity of blood flowing in the hollow fiber membrane is represented as uB. A pressure difference between blood flowing inside the hollow fiber membranes and a fluid flowing outside the hollow fiber membranes is represented as TMP. When a filling blood volume into the hollow fiber membranes per unit membrane area is 20 mL/m2 or more and 35 mL/m2 or less and Jvmax/uB has a value of 0.00015 or more and 0.0006 or less, satisfied is a condition in which a TMP change rate has a value of 0.95 or more and 1.05 or less.
