Use of a compound derived from nitrocatecol, catechol-o-methyltransferase inhibitor for the Prevention and / or treatment of a transthyretin related Amyloidosis
It is provided a catechol-O-methyltransferase (COMT) inhibitor for use in the prevention and/or treatment of transthyretin-associated amyloidosis. It is also provided a catechol-O-methyltransferase (COMT) inhibitor for use in the prevention and/or treatment of transthyretin-associated amyloidosis in combination therapy with another COMT inhibitor, a benzoxazole derivative, iododiflunisal, diflunisal, resveratrol, tauroursodeoxycholic acid, doxocycline, or epigallocatechin-3-gallate.<；p>；La presente invenció；n describe el uso de un inhibidor de catecol-O-metiltransferasa (COMT), donde dicho inhibidor de COMT es un compuesto nitrocatecol con fó；rmula (I) o una sal farmacé；uticamente aceptable del mismo, en donde R se define como en el pliego de reivindicaciones de la solicitud, en la preparació；n de un medicamento ú；til para la prevenció；n y/o tratamiento de una amiloidosis asociada a transtiretina (TTR).<；/p>；
