PERRON, HERVE,BESEME, FREDERIC,BEDIN, FREDERIC,PARANHOS-BACCALA, GLAUCIA,KOMURIAN-PRADEL, FLORENCE,JOLIVET REYNAUD, COLETTE,MANDRAND, BERNARD
申请号：
EP07018564.0
公开号：
EP1916304B1
申请日:
1996.08.02
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
Isolated and purified viral material (A) includes, in the genome, (a) one of 10 sequences given in the specification (from about 400 bp to 2.5 kb)； (b) their complements or (c) sequences equiv. to (a) and (b) and having at least 50, pref. 70, % homology with (a) and (b) over a stretch of 100 contiguous nucleotides. New nucleotide fragments (B) comprise: (i) any complete or partial genomic sequence of the pol gene of virus MSRV-1 (multiple sclerosis related virus), excluding a specified 1158 bp sequence (S1)； (ii) all partial or complete genomic env or gag gene sequence of MSRV-1； (iii) any sequence that overlaps the pol and env or pol and gag genes； (iv) any partial or complete sequence from those 10 sequences from (A) given in the specification, i.e. from the clones FBd3, t pol, JLBc1, JLBc2, GM3, FBd13, LB19, LTRGAG12, FP6 and G+E+A, but excluding sequences identical to, or contg., S1； (v) sequences complementary to the above genomic sequences； (vi) any equiv. sequence； (B) does not comprise or include the ERV (endogenous retroviral)-9 sequence.
