#$%^&*AU2016231508B220181108.pdf#####ABSTRACT An apparatus for extracorporeal treatment of blood comprising: a filtration unit having a primary chamber and a secondary chamber separated by a semi-permeable membrane; a blood withdrawal line connected to an inlet of the 5 primary chamber, and a blood return line connected to an outlet of the primary chamber said blood lines being configured for connection to a patient cardiovascular system; a blood pump configured to control the flow of blood through the blood lines; an effluent fluid line connected to an outlet of the secondary chamber; at least two further fluid lines selected in the group comprising: a pre-dilution infusion fluid line connected at one end thereof to the blood withdrawal line, a post-dilution infusion fluid line connected at one end thereof to the blood return line, a dialysis fluid 10 line connected at one end thereof to the inlet of the secondary chamber, a pre-blood pump infusion fluid line connected at one end thereof to the blood withdrawal line in a region of this latter which is positioned in use upstream the blood pump, means for regulating the flow of fluid through said fluid lines; and a control unit connected to the means for regulating, the control unit being configured to execute a flow-rate setup procedure comprising: allowing entry by an operator of the set value for at least a first fluid flow rate selected in the group including: a fluid flow rate 15 through the pre-dilution infusion fluid line, a fluid flow rate through the post-infusion fluid line, a fluid flow rate through the pre-blood pump infusion fluid line, a fluid flow rate through the dialysis liquid fluid line, and a fluid removal rate from the patient, allowing entry of a set value for a prescribed dose to be delivered, calculating set values of at least a second and a third of the fluid flow rates of said group of flow rates, based on the said first fluid flow rate set by the operator