A method and system are provided for analyzing motion data collected by a cardiovascular navigation system to determine a level of dyssynchrony exhibited by a heart. The method and system comprise obtaining a motion data (MD) set that includes a plurality of map point specific motion data (PSMD) collections of motion data. The motion data in each PSMD collection includes information indicating an amount and direction of motion that occurred at a corresponding map point on a wall of the heart during a select period of time, such as during at least one cardiac cycle. The method and system divide the PSMD collections of data into sectors which may be associated with corresponding phases of the cardiac cycle, and analyze the sectors of the PSMD collections to determine at least one of a slope, a magnitude and a direction of motion at the corresponding map point of the wall of the heart during the associated sector. The method and system assess at least one of the slope, magnitude and direction of motion occurring at the corresponding map points of the wall, and calculate a measure of dyssynchrony in the map points of the wall based on at least one of i) whether the map points move in a select direction during select sectors, ii) whether the map points move by a select amount during the select sectors, iii) a direction of strain waveform during select phases of the cardiac cycle and/or iv) an extent of strain during the select phases.
