SARAH HERZOG MEMORIAL HOSPITAL EZRAT NASHIM ASSOCIATION
发明人:
Uriel HERESCO-LEVY
申请号:
US16677561
公开号:
US20200113894A1
申请日:
2019.11.07
申请国别(地区):
US
年份:
2020
代理人:
摘要:
This invention provides a method of enhancing NMDAR-mediated neurotransmission in a disease associated with NMDAR antibody production, said method comprising administering an NMDAR agonist, an alanine-serine-cysteine transporter inhibitor, a D-amino acid oxidase inhibitor, a glycine transport inhibitor or a combination thereof to said subject. This invention also provides a method of mitigating the severity of, mitigating the pathogenesis of, lowering the incidence of or treating a disease associated with NMDAR antibody production, said method comprising administering an agent, which is an NMDAR agonist, an alanine-serine-cysteine transporter inhibitor, a D-amino acid oxidase inhibitor, a glycine transport inhibitor or a combination thereof to said subject.