Stephanos Ioannidis,Adam Charles Talbot,Bruce Follows,Alexandre Joseph Buckmelter,Minghua Wang,Ann-Marie Campbell,Darby Rye Schmidt,David Joseph Guerin,Justin A. Caravella,R. Bruce Diebold,Anna Ericss
申请号:
US14982127
公开号:
US09902728B2
申请日:
2015.12.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to inhibitors of USP7 inhibitors useful in the treatment of cancers, neurodegenerative diseases, immunological disorders, inflammatory disorders, cardiovascular diseases, ischemic diseases, viral infections and diseases, and bacterial infections and diseases, having the Formula:where m, n, X1, X2, R1-R5, R5′ and R6 are described herein.