STEELE, Keith,WU, Song,HIGGS, Brandon,WIDMAIER, Moritz,ALTHAMMER, Sonja,KORN, Rene,SPITZMUELLER, Andreas
申请号:
EP17870329
公开号:
EP3538142A4
申请日:
2017.11.10
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Provided herein are methods of treating non-small cell lung cancers comprising administering an effective amount of durvalumab (MEDI4736) or an antigen-binding fragment thereof and tremelimumab or an antigen-binding fragment thereof. A combination of durvalumab and tremelimumab was effective at treating non-small cell lung cancers characterized as PD-L1- and having a high level of CD8+ tumor-infiltrating lymphocytes.