The present invention provides an aptamer that binds to an autotaxin, which contains a nucleotide sequence represented by the following formula (I): €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒCGGAACC-N 1 -GGTC€ƒ€ƒ€ƒ€ƒ€ƒ(I) wherein N 1 shows any of 3 to 11 nucleotides, and a utilization method thereof.