A method is for determining a three-dimensional image dataset. In an embodiment, the method includes a first X-ray dataset of the examination volume being received, the first X-ray dataset including a two-dimensional first X-ray projection of the examination volume with respect to a first projection direction; and a second X-ray dataset of the examination volume being received, the second X-ray dataset including a second two-dimensional X-ray projection of the examination volume with respect to a second projection direction. Furthermore, a first three-dimensional image dataset of the examination volume is determined based on the two-dimensional first X-ray projection and the two-dimensional second X-ray projection. An effect of overlaps of vessels with respect to the first projection direction or the second projection direction can be reduced as a result of determining the first three-dimensional image dataset based on the first X-ray dataset and the second X-ray dataset.