BROOKINGS, DANIEL CHRISTOPHER,CALMIANO, MARK DANIEL,GALLIMORE, ELLEN OLIVIA,HORSLEY, HELEN TRACEY,HUTCHINGS, MARTIN CLIVE,JOHNSON, JAMES ANDREW,KROEPLIEN, BORIS,LECOMTE, FABIEN CLAUDE,LOWE, MARTIN ALE
申请号:
CA2874303
公开号:
CA2874303A1
申请日:
2013.06.11
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
A series of benzimidazole derivatives, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.