CLEARY DARRYL G,REYNOLDS CHARLES J,BERREY MIRIAM MICHELLE,HINDES ROBERT G,SYMONDS WILLIAM T,RAY ADRIAN S,MO HONGMEI,HEBNER CHRISTY M,OLIYAI REZA,ZIA VAHID,STEFANIDIS DIMITRIOS,PAKDAMAN ROWCHANAK,CASTE
申请号：
IN4542/DELNP/2014
公开号：
IN2014DN04542A
申请日:
2014.06.05
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
Disclosed herein are a composition and unit dosage form for the treatment of hepatitis C virus (HCV) infection comprising GS 7977 and at least one pharmaceutically acceptable excipient as well as methods for making said composition and unit dosage form. Also disclosed herein is a method of treating a subject preferably a human infected with hepatitis C virus said method comprising administering to the subject for a time period an effective amount of GS 7977 and an effective amount of ribavirin. In one aspect the method comprises administering to the subject an interferon free treatment regimen comprising an effective amount of GS 7977 and an effective amount of ribavirin. In a particular aspect the method is sufficient to produce an undetectable amount of HCV RNA in the subject for at least 12 weeks after the end of the time period.
