It can determine that whether the cancer that object is suffered from is mutated into the positive to ALK the invention discloses those, and/or whether the patient with this cancer has the compound of a relatively slow disease progression process, kit and method, the ALK mutation may generate reaction in a kind of ALK inhibitor for treating Hou. The invention also discloses the processes that those can predict to develop at any time with its state of an illness of the patient of this cancer.本發明公開了那些能確定對象所患的癌症是否對ALK突變成陽性，和／或患有這種癌症的患者是否會有一個相對緩慢的疾病惡化過程的化合物，試劑盒和方法，所述的ALK突變可能在一種ALK抑制劑治療後産生反應。本發明還公開了那些能預測患有這種癌症的患者其病情隨時間發展的進程。
