A positioning method for orthodontic appliance and structure, mainly provided with base units molded by plastic injection. During the fabricating process, a crossed reference line is first drawn on a dental mold of the patient, after heating, the orthodontic appliance is embedded to the base unit, and a flexible member is used to bind and fixedly position the orthodontic appliance. Each of the aforementioned base units together with the orthodontic appliance is attached to the dental mold, and then light curing composite resin is attached to each of the base units. Accordingly, after applying an adhesive layer to each of the orthodontic appliances, each of the series connected base units together with the orthodontic appliances bound to the base units is directly attached to the respective teeth portion of the patient requiring straightening, thereby enabling fitting of orthodontic appliances to be more convenient and providing a more efficient fabricating process.