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Cocaine analogs and methods of preparation and uses thereof
专利权人:
Franklin A. Davis;Naresh Theddu;Maarten E. A. Reith
发明人:
Franklin A. Davis,Naresh Theddu,Maarten E. A. Reith
申请号:
US13475292
公开号:
US08557842B2
申请日:
2012.05.18
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention provides novel cocaine analogs. The invention also provides a method of preparing cocaine analogs with control over the substituents installed at the C-1, C-2, C-3, C-4 and N-8 positions of the tropane bicyclic scaffold. The invention further provides methods of providing anesthesia, blocking reuptake of a monoamine neurotransmitter, and treating depression, by administering to a subject in need of such treatment a pharmaceutical composition comprising a compound of the invention.
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