KORYTKO, ANDREW, IHOR,MARQUIS, DAVID, MATTHEW,SMITH, ERIC, MICHAEL,SWANSON, BARBARA, ANNE
申请号:
HK10105734.8
公开号:
HK1138790B
申请日:
2010.06.09
申请国别(地区):
HK
年份:
2014
代理人:
摘要:
Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.