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Methods of monitoring cellular death using low frequency ultrasound
专利权人:
Michael Kolios
发明人:
Michael Kolios,Gregory J. Czarnota,Michael D. Sherar,Adam Tunis,John Hunt
申请号:
US11455005
公开号:
US08192362B2
申请日:
2006.06.15
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A method of detecting cellular damage within a subject comprises transmitting low frequency ultrasound (20 MHz or below) into a selected site within the subject wherein the selected site has been exposed to a stress capable of causing cellular death at the selected site. At least a portion of ultrasound backscattered from the ultrasound transmitted into the selected site is received. The received backscattered ultrasound is compared to a control backscatter measurement. An increase or a decrease in intensity or spectral slope of the received backscattered ultrasound when compared to the control backscatter measurement indicates cellular death or damage at the selected site within the subject.
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