Satheesh K. Podaralla;Omathanu P. Perumal;Ranjith Kumar Averineni;Mohammed Alqahtani
发明人:
Omathanu P. Perumal,Ranjith Kumar Averineni,Satheesh K. Podaralla,Mohammed Alqahtani
申请号：
US13404536
公开号：
US20120195947A1
申请日:
2012.02.24
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention encompasses nanoparticle assemblies and methods for preparing nanoparticle and compositions comprising such nanoparticles for use in topical or skin applications. The invention further encompasses methods of complexing various molecular and cellular entities to the nanoparticles using the resulting nanoparticles of the invention as delivery devices. The nanoparticles can be used for a variety of applications, such as treating cancer, targeting tumors, reducing the toxicity of a drug in vivo, increasing the efficacy of a complexed agent in vivo, protecting a complexed agent against degradation, increasing skin penetration and retention of drugs, and enhancing the water solubility/dispersibility of a drug or other agent.
