AIHE ZHOU,BING-YAN ZHU,EMILY HANAN,JOSEPH P. LYSSIKATOS,MARK E. ZAK,MICHAEL SIU,PAUL GIBBONS,RICHARD PASTOR,ROHAN MENDONCA,STEVEN R. MAGNUSON,THOMAS E. RAWSON,WENDY LIU
申请号：
BRPI1010197
公开号：
BRPI1010197A2
申请日:
2010.07.02
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R 1 , R 2 and R 3 are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.
