Memorial Sloan Kettering Cancer Center;Massachusetts Institute of Technology
发明人:
CHEAL Sarah M,XU Hong,LARSON Steven M,CHEUNG Nai-Kong,WITTRUP Karl Dane
申请号：
HK18107913
公开号：
HK1248529A1
申请日:
2018.06.20
申请国别(地区):
HK
年份:
2018
代理人:
摘要：
Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.
