Process for the preparation of meso-N-[(3-endo)-8-benzyl-8-azabicyclo[3.2.1]oct-3-yl]acetamide and its derivatives

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专利权人:

JANSSEN PHARMACEUTICA N.V.

发明人:

BACANI, GENESIS, M

申请号：

NZ59985309

公开号：

NZ599853A

申请日:

2009.04.09

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is a method for synthesizing amine E51 comprising an acetylation-reduction of oxime E41 by reacting said oxime E41 with a carboxylic acid anhydride and hydrogen in the presence of a hydrogenation catalyst.

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