#$%^&*AU2016200758A120160225.pdf#####ABSTRACT Embodiments are described for creating and closing tissue access ports or defects, such as transapical access ports, 5 which involve placement of an elongate prosthesis in a helical configuration across the tissue structure site to be crossed, and confirmation that such helical suture configuration is positioned appropriately, before further interventional steps. A plug member may be included to assist with closure of the .0 ports of defects. The elongate prosthesis and plug member may comprise bioresorbable materials. 20
