Long acting VEGF inhibitors and methods of use

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专利权人:

Mary S. Rosendahl

发明人:

Mary S. Rosendahl,George N. Cox, III

申请号：

US12089042

公开号：

US08329866B2

申请日:

2006.10.03

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Disclosed are polymer sFlt-1 conjugates, variants of sFlt-1, compositions comprising such conjugates and variants, including cysteine variants of sFlt-1. Also disclosed is the use of such conjugates, variants and compositions in methods to inhibit the activity of VEGF, to inhibit angiogenesis, and to treat or reduce at least one symptom of diseases and conditions in which it is desirable to inhibit VEGF activity and/or angiogenesis.

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