PYRAZOLYL SUBSTITUTED CARBONIC ACID DERIVATIVES AS MODULATORS OF THE PROSTACYCLIN (PG12) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
TRAN THUY ANH,IBARRA JASON B,SHIN YOUNG JUN,ULLMAN BRETT,ZOU NING,ZENG XI
申请号:
IN4884/DELNP/2011
公开号:
IN2011DN04884A
申请日:
2011.06.24
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
pulmonary arterial hypertension (PAH) and related disorders platelet aggregation coronary artery disease myocardial infarction transient ischemic attack angina stroke ischemia-reperfusion injury restenosis atrial fibrillation blood clot formation in an angioplasty or coronary bypass surgery individual or in an individual suffering from atrial fibrillation atherosclerosis atherothrombosis asthma or a symptom thereof a diabetic-related disorder such as diabetic peripheral neuropathy, diabetic nephropathy or diabetic retinopathy glaucoma or other disease of the eye with abnormal intraocular pressure hypertension inflammation psoriasis psoriatic arthritis rheumatoid arthritis Crohn"s disease transplant rejection multiple sclerosis systemic lupus erythematosus (SLE) ulcerative colitis ischemia-reperfusion injury restenosis atherosclerosis acne type 1 diabetes type 2 diabetes sepsis and chronic obstructive pulmonary disorder (COPD).