A system for hands-free collection of biomaterials, such as urine, in a vessel disposed below a closable port, the vessel being sealable by an at least partially automated sealing mechanism, the sealed vessel being transferable to a storage area. In general terms this application is directed to a hands-free, biomaterial collection system that is it least partially automated. In one aspect, a biomaterial collection system comprises a biomaterial capture area including a port, a collection area disposed below the capture area, a vessel disposed in the collection area and aligned with the port, and a sealing mechanism disposed in the collection area for sealing the vessel.