GILLESPIE, JOSEPH;SAKASE, TAKAO;NEUTRON THERAPEUTICS INC.;SMICK, NOAH;PARK, WILLIAM H. JR.;LAMBERT, MARK
发明人:
PARK, WILLIAM H. JR.,LAMBERT, MARK,GILLESPIE, JOSEPH,SMICK, NOAH,SAKASE, TAKAO
申请号：
CA3065504
公开号：
CA3065504A1
申请日:
2017.06.05
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Design and making methods of a neutrons generating target are described. In some embodiments, a surface of a target substrate can be modified to form one or more surface features. In some embodiments, a neutron source layer can be disposed on the surface of the target substrate. In some embodiments, the neutron source layer and the target substrate can be heated to an elevated temperature to form a bond between the two. In some embodiments, the surface modification of the target substrate can reduce blistering and material exfoliation in the target. The target can be used in boron neutron capture therapy.
